Examples of vaccines, thermapeutic and diagnostic products on the market (as of July 1998) and under development, made using animal cell technology
|
|
On the Market
|
| Product: |
| Human Vaccines: |
| * rabies |
* rubella |
| * hepatitis-B** |
* mumps |
| * polio |
* varicella zoster |
| * hepatitis A |
* yellow fever |
| * adenovirus |
* tick born encephalitis |
| * measles |
* Japanese encephalitis |
| * dengue |
|
|
Veterinary Vaccines: |
| * foot and mouth disease |
* Marek's disease |
| * Aujeszky's disease/pseudorabies |
* dog parvovirus |
|
Therapeutics: |
Indication: |
| * tissue plasminogen activator (tPA) |
pulmonary embolism & acute myocardial infarction |
| * erythropoietin |
anemia associated with kidney failure, cancer & AIDS |
| * interferon alpha* |
cancer & viral diseases |
| * factor VIII |
hemophilia A |
| * factor IX |
hemophilia B |
| * human growth hormone* |
growth deficiency in children |
| * monoclonal antibody |
reversal of organ transplant rejection |
| * monoclonal antibody |
non-Hodgkins lymphoma |
| * monoclonal antibody |
growth deficiency in children |
| * human growth hormone* |
respiratory syncytial virus |
| * granulocyte CSF |
neutropenia |
| * DNAse |
cystic fibrosis |
| * glucocerebrosidase |
type I Gaucher's disease |
|
Therapeutics: |
Indication: |
| * diagnostic monoclonal antibodies |
imaging agents for a variety of diseases, including colorectal, prostate & ovarian cancer |
|
* Significant amounts are produced in bacteria
** Principally produced in yeast
|
|
Under Development
|
| Product: |
Indication: |
| The lists shown here is not exhaustive |
| * factor VII, factor IX |
haemophilia |
| * growth factors & hormones |
cancer, wound healing, infections, bone narrow transplantation, growth disorders, polycystic ovarian disease |
| * follicle stimulating hormone |
treatment of infertility |
| * interleukins |
cancer, blood cell disorders, inflammation |
| * fibrinolytic enzymes |
dissolution of blood clots |
| * vaccines |
AIDS, herpex simplex & others |
| * CD4 immunoadhesins |
AIDS |
| * monoclonal antibodies including genetically engineered antibodies |
treatment & diagnosis of cancer, sepsis, Rheumatoid arthritis, Crohn's & other diseases |
| * soluble receptors |
cancer, infections, inflammation, sepsis |
| * gene therapy vectors |
gene therapy of cancer,cystic fybrosis etc. |
| * stem cell expansion |
somatic cell therapy |
| * tissue engineering |
artificial organs |
