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ACTIP Bulletin 13

March 1999

Special edition on the 5th Framework Programme




Official launch 5th Framework Programme

 

Last week, on February 25 and 26, the Services of the European Commission officially launched the 5th Framework Programme (FP). This 5th Framework Programme is not only intended for research in the Life Sciences, but regulates ALL research to be funded by the European Union in the period 1998-2002. The event, which attracted more than 4,000 participants from all over Europe, gave an excellent overview of the 5th FP, its objectives, the various Work Programmes and guidelines for proposals. Below you will find my (Helma Hermans') interpretation of the presentations and the distributed documentation. All errors are mine.


Documentation

 

Most of the documents distributed during the conference were still preliminary, but the final documents will not be too much different. The Secretariat of DG 12 has promised me to send all of you a full set of documentation; if you cannot wait for that, the full text of the 5th Framework Programme and of the Specific Work Programmes is also available from:

http://www.cordis.lu/fp5/home.html

or contact the Programme Information desk, life@dg12.cec.be, fax 00 32 2 299 18 60.

Remember, when you think of submitting a proposal, always rely on the official texts as published in the Official Journal of the European Communities. The text of calls is also published on the CORDIS website.


A useful general start is the booklet 'The Fifth Framework Programme, the research programmes of the European Union, 1998-2002 (catalogue number EUR 18764). It gives the principal characteristics of the Fifth Framework Programme and lists all thematic and horizontal programmes, including the key actions, the generic research and the support for research infrastructures to be found in each programme. In addition, it gives the programmes of Euratom and the Joint Research Centre. The booklet also helps you to identify which thematic or horizontal programmes might be of interest to you - do browse, because interesting elements can be found in all programmes. For example, in horizontal programme 2 there are special measures for SME's and technology transfer, and in horizontal programme 3 there is much emphasis on training and mobility of researchers and access to research facilities.

According to this booklet, the breakdown of the budget is:
• Thematic programme 1, Quality of life and management of living resources: 2413 Million EURO
• Thematic programme 2, User-friendly information society: 3600 million EURO
• Thematic programme 3, Competitive and sustainable growth: 2705 million EURO
• Thematic programme 4, Energy, environment and sustainable development: 2125 million EURO
• Horizontal programme 5, Confirming the international role of Community research: 475 million EURO
• Horizontal programme 6, Promotion of innovation and encouragement of participation of SMEs: 363 million EURO
• Horizontal programme 7, Improving human research potential and the socio-economic knowledge base: 1280 million EURO
• Joint Research Centre, direct actions: 739 million EURO
• Euratom: 979 million EURO


For thematic programme 1, Quality of Life and management of living resources, the specific Work Programme and the Guide for Proposers are useful starting points (for each programme there will be a guide for proposals). It was emphasized by various speakers that the 5th FP is a break with the past, in particular in the Life Sciences area. The central theme is "Quality of Life", and objectives have been formulated to meet such quality with respect to individual health, the environment, the quality and safety of the food supply, and the quantity and quality of employment. These objectives are:
* meeting socio-economic needs
* increasing European added value
* supporting European competitiveness
This might all seem a bit vague, but if you read the Work Programme you will find plenty of examples how these objectives can be translated into research targets. Again, various speakers emphasized that the 5th FP is a broad framework in which research targets can be pursued, instead of a scientific shopping list. Some went even further and said one should not despair if you have a good research proposal but the specific topic is not mentioned in the Work Programme: as long as the research proposed is of high quality and the proposal addresses the three objectives above (socio-economic needs, added value and employment/competitiveness), there is nothing to prevent you from being taken serious. Let's see how this works in practice, but it certainly gives some extra freedom and challenges.

The Work Programme will be revised annually, and based on external advice, i.e. from the External Advisory Groups, priorities will be selected annually. This will create more flexibility. As an Industrial Platform we should discuss with the Commision officials what the role of a platform can be in the selection of priorities.


The Guide for Proposers for the Quality of Life programme is a useful document outlining not only the various key actions etc. but also who can participate, how to submit a proposal, how it will be evaluated and selected, etc etc. At the back, it contains a list of Scientific Officers responsible for the various key actions, generic activities and infrastructure support.

 

 

Submitting a proposal

 

Depending on the type of action and the programme, one or more legal entities should submit the proposal. RTD proposals normally require at least two participants from two different EU members states or associated countries. Groups from the USA, Canada, Switzerland, Australia, South Africa etc may collaborate in a project, but they will NOT be funded.

If you intend to submit a proposal, you will need:
* the Work Programme for the Specific Programme you are applying for
* the Call for Proposals as published in the Official Journal or on CORDIS
* the Guide for Proposers
* the Evaluation Manual (detailing selection criteria)

The Commission has prepared a software Proposal Preparation Tool. They say it can be downloaded from:

http://147.67.24.10/ppt/

but I tried it on Tuesday March 2 and unfortunately it then came up blanco. Maybe it will be put up this week.

The Tool, called Protool, requires a browser with a graphic interface, preferably Netscape Navigator or Internet Explorer.

One of the speakers advised to proceed as follows if one wants to submit a proposal:
(1) identify your target with advice from the end users
(2) bring together the necessary disciplines
(3) integrate product or process development right from the start
(4) this will lead to both new horizons in product and process development as well as to new horizons in fundamental research.

But it was also said that addressing all the objectives formulated in the 5th FP will be a learning process including all partners, such as researchers, industry, users/consumers and science management.


 

Calls for Proposals

 

There will be 3 types of Calls for Proposals:
1. Periodic Calls, for submissions for RTD projects and related activities. Have a defined scope and a fixed deadline. Published in the Official Journal.
2. Open calls, launched at the start of the programme and open until the last year of the 5th FP. For SME specific measures, support for Research Infrastructures, training, international activities, thematic networks and accompanying measures.
3. Dedicated calls, published once or twice a year in the Official Journal and limited to very specific topics or activities. The Commision may also publish a request for interested parties (Expression of Interest/Needs) to suggest for ideas that could be included.
The first Call for Proposals will be issued in the Official Journal of March 2, 1999 (but verbally it was said 6 or 8 March, so please check the Official Journal and the websites of DG 12 and CORDIS). Most areas will have 3 calls for proposals between 1999 and 2002.
The deadline depends on the Priority topics, but for
1999 there will be deadlines in June (June 1, 8 or 15) and October (4, 11 or 18).
For topics of most interest to our Platform members, the following deadlines have been set:

Key action 2, Control of Infectious Diseases;

Available budgets: June deadline 64 million EURO; October deadline, 54 million EURO

Deadline June 1:
2.1. Development of vaccines

Deadline October 11:
2.2. New strategies for treatment and prevention
2.3. Public health issues

Key action 3, the Cell factory

Available budgets: June deadline, 75 million EURO; October deadline, 36 miilion EURO

Deadline June 1:
3.1.1. New diagnostics and therapeutics (incl. gene therapy)
3.1.2. Biological productions
3.1.3. Novel In Vitro testing as alternatives to Animal Testing
3.3.2. Products and processes involving/derived ffrom microbes, plants and animals (incl. fermentation, downstream processing)
3.3.3. Functional biomolecules

Deadline June 15:
6.1 - 6.5: Diverse topics from the key action 'The ageing population and disabilities

Deadline October 18:
3.3.1. Exploiting cellular and molecular characteristics of organisms
3.3.4. Metabolic and genetic diversity

Generic research:

Deadline June 1:
7.1. Research on molecular, genetic, environmental and life style
factors
8.1/8.2. Meaning of the genome information; structural studies
9.1/9.2: Cell communication, brain theories
10.2 Fighthing drug-related problems
12. Biomedical ethics and bioethics
13. Socio-economic aspects

Deadline October 11:
7.2/7.3. Evaluation of therapies: databases, registries, sample banks
8.3/8.4 Novel expression systems; biophysics, statistics and
computation
9.3/9.4 Brain development, behaviour, cognition and functional mapping
10.1 Improving of health systems
12. Biomedical ethics and bioethics
13. Socio-economic aspects

Predictive toxicity testing (area 4.2.2) will have a call at the end of this year. That call will close in February 2000.

Open call: area 14, support for research infrastructures

Budget: 1999: 20 million EURO; 2000: 16 miilion EURO; 2001: 16 million EURO; 2002: 8 million EURO
Please note that there will not be funding for research, only for coordination of linkages between existing institutions and existing data.

Open, every year:
Clinical research facilities, notably:

* facilities for development and validation of drugs, vaccines, methods and devices for improved diagnosis, monitoring and therapy

* European warning system for communicable diseases

* Advanced medical technology facilities and infrastructures for standardised multi-centre clinical trials

* Registries and pooled databases of clinical trials

* European facilities for batch production for clinical trials

* Preclinical research facilities, notably: facilities for the development of in vitro systems or cell cultures and, where no other means exist, breeding of animals, to provide models of human diseases and facilitate development of vaccines, new drugs and medical devices.


 

Funding

 

The implementation measures that will be funded and the research areas covered will vary from call to call, so please see the Offical Journal and specific Guides for Proposers.

The following actions can be supported:
* shared-costs actions for R&D projects (50% of eligible costs, max 48 months), demonstration projects (35%, max 48 months), combined R&D and demonstration projects (35-50%, max 48 months), support for access to research infrastructures (100%), SME cooperative research projects (50%, max 24 months, min 3 SMEs from min 2 member states), SME exploratory awards (75%, max 12 months, SMEs only)

* training (individual and host) fellowships (100%, max 24 or 36 months)

* research training networks (100%)

* thematic networks (100%, max 48 months) (i.e. for cluster projects, or platforms coordinating exploitation of results)

* concerted actions for existing RTD projects (100%, max 4 years)

* accompanying measures (100%)


 

New: cluster projects

 

New are the Cluster projects, which are defined groups of RTD projects, aimed at complementarity and facilitating the exploitation of the results. According to several speakers, a cluster project is not a large RTD project but a group of projects providing a certain critical mass. The intention is that a topic is addressed from different aspects, for example, both basic knowledge, clinical experience, manufacturing, individual interest/patient groups. All types of projects can be assembled and integrated with a cluster, including those funded by different RTD activities.


 

Evaluation of the proposals

 

After an eligibility check (watch this, some say as many as 20% of proposals is rejected because they are incomplete!), the project is evaluated on scientific excellence and quality of management. If the proposal survives this phase, it will be evaluated by a larger panel of independent experts who will assess: the contribution to societal needs, the community added value and the economic and social development aspects. Thus, while projects in FP 4 were mainly judged on meeting the scope of the science as described in the Work Programme, in FP 5 the proposals will have to match the socio-economic objectives of the key actions, as described in the Work Programmes. In words of one of the speakers: in FP 4, a wealth of information was generated; FP 5 offers a lens that focuses that wealth of information on issues of importance. Also, a major issue is linking the ability to discover to the ability to produce.


 

Programme contact points

 

The Guide for Proposers gives the following contact points for areas of interest to our platform:

Key action 2, control of infectious diseases:
Vaccine development, therapeutic interventions (incl. TSE): Arnd Hoeveler
Vaccine development, therapeutic interventions (incl. TSE), public health: Joachim Hombach

Key action 3, cell factory:
New diagnostics and therapeutics, biological productions: Irene Norstedt
Alternatives to animal testing: Beatrice Lucaroni
Cellular and molecular characteristics, functional biomolecules: Philippe de Taxis du Poet
Metabolic and genetic diversity: Charles Kessler

Key action 4, toxicological methods: Alain Van Vossel, Laurent Bontoux

Key action 6, ageing population: Philippe Jehenson

Generic activities, neurosciences: Line Matthiessen

Support for research infrastructures: Shaid Baig

Coordination of policies and actions: Maurice Lex

Communication: Stephane Hogan

Innovation and SME: Waldemar Kuett


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